Clinical Topics

July 2017 Vol. 12 No. 7

August 3, 2017 – The U.S. Food and Drug Administration today approved Mavyret (glecaprevir and pibrentasvir) to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis, including patients with moderate to severe kidney disease and those who are on dialysis . . .

July 2017 Vol. 12 No. 7

Cadmium exposure and endometrial cancer risk: A large midwestern U.S. population-based case-control study.

Estrogen-mimicking chemicals, such as cadmium, may be associated with increased susceptibility to hormone-dependent cancers, though supporting data are sparse, particularly for endometrial cancer. The Health and Environmental Exposure Research (HEER) study worked . . .

July 2017 Vol. 12 No. 7

August 3, 2017 – The U.S. Food and Drug Administration today expanded the approval of Imbruvica (ibrutinib) for the treatment of adult patients with chronic graft versus host disease (cGVHD) after failure of one or more treatments. This is the first FDA-approved therapy for the treatment of cGVHD.

cGVHD . . .

July 2017 Vol. 12 No. 7

Protecting American Families: Comprehensive Approach to Nicotine and Tobacco

Remarks by Scott Gottlieb, M.D. / Commissioner of Food and Drug Administration
July 28, 2017 / White Oak, MD

Tobacco use remains the leading cause of preventable disease and death in the United States. But much has changed in the landscape of . . .

July 2017 Vol. 12 No. 7

Pneumonia or sepsis in adults associated with increased risk of cardiovascular disease.
Sophia Antipolis, 2 August 2017: Pneumonia or sepsis in adults that results in hospital admission is associated with a six-fold increased risk of cardiovascular disease in the first year, according to research published today in the European . . .

July 2017 Vol. 12 No. 7

On July 20, the U.S. Food and Drug Administration (FDA) cleared Embrace Neonatal MRI System, the first magnetic resonance imaging (MRI) device specifically for neonatal brain and head imaging in neonatal intensive care units. Read more . . .

July 2017 Vol. 12 No. 7

Obese patients who undergo bariatric surgery are more like to achieve a body mass index (BMI) of less than 30 one year after surgery if they have a BMI of less than 40 before surgery, according to a study published by JAMA Surgery. Read more . . .

July 2017 Vol. 12 No. 7

On July 18, the U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis. Vosevi is a fixed-dose, combination tablet containing two previously approved drugs – sofosbuvir and velpatasvir – and a . . .

July 2017 Vol. 12 No. 7

Decades before people with Alzheimer’s disease develop memory loss and confusion, their brains become dotted with plaques made of a sticky protein – called amyloid beta – that is thought to contribute to the disease and its progression.

Currently, the only way to detect amyloid beta in the brain is via . . .

Researchers develop method that could one day be used in brain trauma lawsuits
Lawyers representing both sides in concussion lawsuits against sports leagues may eventually have a new tool at their disposal: a diagnostic signature that uses artificial intelligence to detect brain trauma years after it has occurred.

While the . . .

July 2017 Vol. 12 No. 7

On July 7, the U.S. Food and Drug Administration (FDA) approved Endari (L-glutamine oral powder) for patients age 5 years and older with sickle cell disease to reduce severe complications associated with the disorder. Read more . . .