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Does folic acid really prevent pre-eclampsia?

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By: Julie Cullen

By Julie Cullen, Managing Editor, American Nurse Today

The answer to that question, it turns out, is no. A recent randomized trial found that high-dose folic acid does not prevent pre-eclampsia. The study, published in BMJ, included a group of 2,464 women who had at least one risk factor for pre-eclampsia. Half received 4.0 mg of folic acid a day and half got a placebo and 1.1 mg of folic acid. The result was no difference in the incidence of pre-eclampsia or any other negative outcome the researchers tracked.

Some people might say, why not just go ahead and take the high dose. But I like what the senior author, Dr. Mark C. Walker, said in response to that question: “There are so many times in medicine where things go from panacea to prescription to poison. I’m advising people to take a regular multivitamin, and that’s it.”

Sources: The New York Times

The views and opinions expressed here are those of the author and do not necessarily reflect the opinions or recommendations of the American Nurses Association, the Editorial Advisory Board members, or the Publisher, Editors and staff of American Nurse Journal. This has not been peer reviewed.

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