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Which diagnostic biomarker is detectable in the urine within 12 hours after renal tubular cells are injured?
a. Neutrophil gelatinase-associated lipocalin
b. Cystatin C
c. Tissue inhibitor metalloproteinase-2
d. Glomerular filtration rate

Answer to Quiz Time: c. Tissue inhibitor metalloproteinase-2 (TIMP-2) appears in the urine within 12 hours after renal tubular cells are injured from ischemia or sepsis. In one study, urinary TIMP-2 testing showed certain patients had seven times the risk of developing acute kidney injury.

Learn more by reading the continuing nursing education article “Acute kidney injury: Causes, phases, and early detection.”


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